Monday, June 1, 2020

Difference between MIC and MBEC for antibiotic experiments

MIC - Minimal inhibition concentration

The minimal concentration of antibiotic at which no bacterial growth is observed is called MIC. For instance, MIC of colistin for Pseudomonas aeruginosa ranges 1-2 ug/ml. The strains which can grow above MIC may be considered resistant or tolerant strains.

MBEC- Minimal Biofilm Eradication Concentration

The minimum concentration of antibiotic required to eradicate mature biofilms is termed as MBEC. In general, MBEC are higher than MIC e.g. Pseudomonas aeruginosa MBEC ranges >100 ug/ml colistin. 
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 https://pubmed.ncbi.nlm.nih.gov/34332222/

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     https://pubmed.ncbi.nlm.nih.gov/34332222/
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     One recent review article discussing Bacillus subtilis community life is most interesting to read. The review suggests how this bacterium ...
  • Difference between MIC and MBEC for antibiotic experiments
    MIC - Minimal inhibition concentration The minimal concentration of antibiotic at which no bacterial growth is observed is called MIC. Fo...