Saturday, May 30, 2020

Antibiotic resistance and biofilms?

Share your thoughts on why biofilms are antibiotic-resistant?


  • Restricted penetration
  • resistant cells
  • persisitors

Friday, May 29, 2020

Best articles nature rev microbiology on biofilms

Free cell or planktonic cells, biofilms, dispersed cells

To understand the concept of biofilms we must know three phenotypes of bacteria

  • Planktonic cells- These are free cells or free-floating cells. In other words, they are not attached to any surfaces. Examples- culturing bacteria in the flask (in the lab) with 200 rpm, acute bacterial infection in the blood.
  • Biofilms- These are surface-attached bacteria. The biofilm formation may be divided into phases- initiation includes a bacterial approach to surface and adhering, followed by microcolony formation, mature biofilms 
  • Dispersed cells- these are bacterial cells which come out from biofilms. This part is not very very clear amongst the biofilm world.

 https://pubmed.ncbi.nlm.nih.gov/34332222/